The past two months has seen the addition of six new comedications, the renaming of two existing comedications and 34 interaction colour changes.
Six new comedications have been added and are listed below:
- Cyproterone acetate (2 mg or less) [Contraceptives/HRT]
- Orforglipron [Other]
- Rifapentine (weekly) [Antibacterials]
- Suzetrigine [Analgesics]
- Tradipitant [Gastrointestinal Agents]
- Zoliflodacin [Antibacterials]
A couple of comedications have been renamed as a result of these new additions.
- Rifapentine renamed to Rifapentine (daily)
- Cyproterone renamed to Cyproterone (50 mg and above)
Several interaction colour changes have been made in response to updated information and/or for consistency.
- “Upgrades” - amber to red
- Midostaurin with lenacapavir (ARV and PrEP)
- Bromocriptine with atazanavir alone, ritonavir and boosted ARVs - “Downgrades” - red to amber
- Rifabutin with bictegravir/emtricitabine/tenofovir alafenamide
- Rifampicin with bictegravir/emtricitabine/tenofovir alafenamide - “Downgrades” - yellow to green
- Rifapentine (weekly) with raltegravir
- Etonogestrel (implant), medroxyprogesterone (depot injection) and norethisterone (IM depot injection) with lenacapavir
- Tecovirimat with lenacapavir (ARV and PrEP), tenofovir-DF or combinations containing tenofovir alafenamide or tenofovir-DF
- Tenofovir alafenamide (HBV) with lenacapavir
- Pitolisant with bictegravir/emtricitabine/tenofovir alafenamide
- Carbimazole with bictegravir/emtricitabine/tenofovir alafenamide
